MOLECULAR FEATURES OF INTERACTION BETWEEN VEGFA AND ANTI-ANGIOGENIC DRUGS USED IN RETINAL DISEASES: A COMPUTATIONAL APPROACH

Molecular features of interaction between VEGFA and anti-angiogenic drugs used in retinal diseases: a computational approach

Anti-angiogenic agents are biological drugs used for treatment of retinal neovascular degenerative diseases.In this study, we aimed at in-silico analysis of Soccer - Goalie - Gloves interaction of vascular endothelial growth factor A (VEGFA), the main mediator of angiogenesis, with binding domains of anti-angiogenic agents used for treatment of ret

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Battered Child Syndrome

The World Health Organization defines the battered child syndrome as every form of physical and/or emotional mistreatment, sexual abuse, abandonment or negligent treatment, exploitation with a commercial aim or of any other type, resulting in a real or potential damage to Keepsake Pins health, survival, development and dignity of children in the co

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Facile Synthesis of Ternary Boron Carbonitride Nanotubes

Abstract In this study, a novel and facile approach for the synthesis of ternary boron carbonitride (B–C–N) nanotubes was LIGHTERS reported.Growth occurred by heating simple starting materials of boron powder, zinc oxide powder, and ethanol absolute at 1150 °C under a mixture gas flow of nitrogen and hydrogen.As substrate, commerci

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Unravelling Antigenic Cross-Reactions toward the World of Coronaviruses: Extent of the Stability of Shared Epitopes and SARS-CoV-2 Anti-Spike Cross-Neutralizing Antibodies

The human immune repertoire retains the molecular memory of a very great diversity of target antigens (epitopes) and can recall this upon a second encounter with epitopes against Acrylic Board Wall Art which it has previously been primed.Although genetically diverse, proteins of coronaviruses exhibit sufficient conservation to lead to antigenic cro

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Crosslinking substrate regulates frictional properties of tissue-engineered cartilage and chondrocyte response to loading

Abstract Hydrogels are frequently used in regenerative medicine due to their hydrated, tissue-compatible nature, and tuneable mechanics.While many strategies enable bulk mechanical modulation, little attention is given to tuning surface tribology, and its impact on cellular behavior under mechanical stimuli.Here, we demonstrate that photocrosslinki

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